Research/art/teacher profile of a person

I. - Basic information

I.1 - Surname

Varhač

I.2 - Name

Rastislav

I.3 - Degrees

doc., RNDr., PhD.

I.4 - Year of birth

1976

I.5 - Name of the workplace

Pavol Jozef Šafárik University in Košice, Faculty of Science, Institute of Chemistry

I.6 - Address of the workplace

Moyzesova 11, 040 01 Košice

I.7 - Position

Teacher

I.8 - E-mail address

rastislav.varhac@upjs.sk

I.9 - Hyperlink to the entry of a person in the Register of university staff

https://www.portalvs.sk/regzam/detail/14675

I.10 - Name of the study field in which a person works at the university

Chemistry

I.11 - ORCID iD

https://orcid.org/0000-0001-5497-4511

II. - Higher education and further qualification growth

II.1 - First degree of higher education

II.2 - Second degree of higher education

II.a - Name of the university or institution

Pavol Jozef Šafárik University in Košice, Faculty of Science

II.b - Year

1999

II.c - Study field and programme

Chemistry, Biochemistry

II.3 - Third degree of higher education

II.a - Name of the university or institution

Pavol Jozef Šafárik University in Košice, Faculty of Science

II.b - Year

2005

II.c - Study field and programme

Biochemistry

II.4 - Associate professor

II.a - Name of the university or institution

Pavol Jozef Šafárik University in Košice, Faculty of Science

II.b - Year

2022

II.c - Study field and programme

Biochemistry

II.5 - Professor

II.6 - Doctor of Science (DrSc.)

III. - Current and previous employment

III.a - Occupation-position	III.b - Institution	III.c - Duration
Teaching staff	Pavol Jozef Šafárik University in Košice, Faculty of Science, Institute of Chemistry	01.04.2022 - up to now
Research Associate	Pavol Jozef Šafárik University in Košice, Faculty of Science, Institute of Chemistry	01.07.2010 - 31.03.2022
Postdoctoral Research Associate	The University of Texas Health Science Center at San Antonio, U.S.A., Department of Biochemistry	June 2008 - May 2010
Research Associate	Pavol Jozef Šafárik University in Košice, Faculty of Science, Institute of Chemistry	01.01.2007 - 31.12.2008
Research Scholar	École Polytechnique Fédérale de Lausanne, Switzerland	October 2004 - July 2005
Research Assistant	Slovak Academy of Sciences, Institute of Experimental Physics, Department of Biophysics, Košice	01.10.2002 - 31.12.2006

IV. - Development of pedagogical, professional, language, digital and other skills

IV.a - Activity description, course name, other	IV.b - Name of the institution	IV.c - Year
Intensive Language Course (French language)	Université de Fribourg, Switzerland	2004

V. - Overview of activities within the teaching career at the university

V.1 - Overview of the profile courses taught in the current academic year according to study programmes

V.1.a - Name of the profile course	V.1.b - Study programme	V.1.c - Degree	V.1.d - Field of study
Proteins, Structure and Function	Biochemistry	II.	Chemistry
Trends in Biophysical Chemistry	Biochemistry	III.	Chemistry

V.2 - Overview of the responsibility for the delivery, development and quality assurance of the study programme or its part at the university in the current academic year

V.3 - Overview of the responsibility for the development and quality of the field of habilitation procedure and inaugural procedure in the current academic year

V.4 - Overview of supervised final theses

V.4.1 - Number of currently supervised theses

V.4.a - Bachelor's (first degree)

V.4.b - Diploma (second degree)

V.4.c - Dissertation (third degree)

V.4.2 - Number of defended theses

V.4.a - Bachelor's (first degree)

V.4.b - Diploma (second degree)

V.4.c - Dissertation (third degree)

V.5 - Overview of other courses taught in the current academic year according to study programmes

V.5.a - Name of the course	V.5.b - Study programme	V.5.c - Degree	V.5.d - Field of study
Biochemistry Practical	Chemistry	I.	Chemistry
Practical Course in Biophysics of Proteins and Nucleic Acids	Biophysics	II.	Biophysics
Semestral Project I	Biochemistry	II.	Chemistry
Semestral Project II	Biochemistry	II.	Chemistry
Experimental Methods to Master´s Thesis	Biochemistry	II.	Chemistry
Laboratory Practices to Master's Thesis	Biochemistry	II.	Chemistry
Fundamentals of Regulatory Processes in Biosystems	Chemistry	I.	Chemistry
Biochemical Analytical Methods	Biochemistry	II.	Chemistry
Methodical Procedures of Experimental Work	Biochemistry	III.	Chemistry

VI. - Overview of the research/artistic/other outputs

VI.1 - Overview of the research/artistic/other outputs and the corresponding citations

VI.1.1 - Number of the research/artistic/other outputs

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.2 - Number of the research/artistic/other outputs registered in the Web of Science or Scopus databases

VI.1.a - Overall

VI.1.b - Over the last six years

VI.1.3 - Number of citations corresponding to the research/artistic/other outputs

VI.1.a - Overall

153

VI.1.b - Over the last six years

VI.1.4 - Number of citations registered in the Web of Science or Scopus databases

VI.1.a - Overall

153

VI.1.b - Over the last six years

VI.1.5 - Number of invited lectures at the international, national level

VI.1.a - Overall

VI.1.b - Over the last six years

VI.2 - The most significant research/artistic/other outputs

Garajová, K.; Balogová, A.; Dušeková, E.; Sedláková, D.; Sedlák, E.; Varhač, R.: Correlation of lysozyme activity and stability in the presence of Hofmeister series anions. Biochimica et Biophysica Acta - Proteins and Proteomics. 1865 (3), 2017, 281-288. WOS Q2, IF 2.609, citations: 19.

Varhač, R.; Tomášková, N.; Fabian, M.; Sedlák, E.: Kinetics of cyanide binding as a probe of local stability/flexibility of cytochrome c. Biophysical Chemistry. 144 (1-2), 2009, 21-26. WOS Q2, IF 2.276, citations: 24.

Tomášková, N.; Varhač, R.; Žoldák, G.; Olekšáková, L.; Sedláková, D.; Sedlák, E.: Conformational stability and dynamics of cytochrome c affect its alkaline isomerization. Journal of Biological Inorganic Chemistry. 12 (2), 2007, 257-266. WOS Q1, IF 3.325, citations: 8.

Varhač, R.; Antalík, M.; Bánó, M.: Effect of temperature and guanidine hydrochloride on ferrocytochrome c at neutral pH. Journal of Biological Inorganic Chemistry. 9, 2004, 12-22. WOS Q1, IF 3.300, citations: 23.

Varhač, R.; Antalík, M.: Determination of the pK for the Acid-Induced Denaturation of Ferrocytochrome c. Biochemistry. 43, 2004, 3564-3569. WOS Q1, IF 4.008, citations: 5.

VI.3 - The most significant research/artistic/other outputs over the last six years

Felčíková, K.; Hovan, A.; Polák, M.; Loginov, D. S.; Holotová, V.; Díaz, C.; Kožár, T.; Lee, O. S.; Varhač, R.; Novák, P.; Bánó, G.; Sedlák, E.: Design of AsLOV2 domain as a carrier of light-induced dissociable FMN photosensitizer. Protein Science. 33, 2024, e4921 (s. 1-15). WOS Q1, IF 4.5, citácie: 1.

Lukáčová Bujňáková, Z.; Melnyk, I. V.; Dutková, E.; Varhač, R.; Jakubíková, J.; Cholujová, D.; Tóthová, E.; Storozhuk, L.; Briančin, J.: Nano-bio interface between As4S4 nanoparticles and albumin influenced by wet stirred media milling. International Journal of Pharmaceutics. 640, 2023, art.no. 123046 (s. 1-12). WOS Q1, IF 5.3, citácie: 0.

Lukáčová Bujňáková, Z.; Dutková, E.; Jakubíková, J.; Cholujová, D.; Varhač, R.; Borysenko, L.; Melnyk, I. V.: Investigation of the Interaction between mechanosynthesized ZnS nanoparticles and albumin using fluorescence spectroscopy. Pharmaceuticals. 16, 2023, art. no. 1219 (s. 1-25). WOS Q1, IF 4.3, citácie: 0.

Sedlák, E.; Kožár, T.; Varhač, R.; Musatov, A.; Tomášková, N.: Anion-specific effects on the alkaline state of cytochrome c. Biochemistry (Moscow). 86, 2021, 59-73. WOS Q4, IF 2.824, citácie: 1.

Petrenčáková, M.; Varhač, R.; Kožár, T.; Nemergut, M.; Jancura, D.; Schwer, M.-S.; Sedlák, E.: Conformational properties of LOV2 domain and its C450A variant within broad pH region. Biophysical Chemistry. 259, 2020, art.no. 106337, 1-9. WOS Q3, IF 1.995, citácie: 2.

VI.4 - The most significant citations corresponding to the research/artistic/other outputs

Cited output: Varhač, R.; Tomášková, N.; Fabian, M.; Sedlák, E.: Kinetics of cyanide binding as a probe of local stability/flexibility of cytochrome c. Biophysical Chemistry. 144 (1-2), 2009, 21-26.

Citation: Kokhan O.; et al.: J. Biol. Chem. 285, 2010, 22522-22531. WOS Q1, IF 5.328.

Citation: Lo Nostro P.; Ninham B. W.: Chem. Rev. 112, 2012, 2286-2322. WOS Q1, IF 41.298.

Citation: Salis A. T.; Ninham B. W.: Chem. Soc. Rev. 43, 2014, 7358-7377. WOS Q1, IF 33.383.

Citation: Mazzini V.; Craig V. S. J.: Curr. Opin. Colloid Interface Sci. 23, 2016, 82-93. WOS Q1, IF 6.136.

Citation: Gong X.; et al.: Anal. Chem. 91, 2019, 1826-1837. WOS Q1, IF 6.785.

VI.5 - Participation in conducting (leading) the most important research projects or art projects over the last six years

APVV-23-0013, 2024-2028, participation

APVV-20-0340, 2021-2025, participation

VEGA 1/0074/22, 2022-2024, participation

VEGA 2/0009/17, 2017-2020, participation

VII. - Overview of organizational experience related to higher education and research/artistic/other activities

VII.a - Activity, position	VII.b - Name of the institution, board	VII.c - Duration
Departmental Erasmus+ Coordinator	ÚCHV PF UPJŠ in Košice	April 2013 - up to now
Deputy for research	ÚCHV PF UPJŠ in Košice	September 2018 – November 2019, April 2013 – October 2015
Member of the ŠVK expert jury in the Biochemistry section	ÚCHV PF UPJŠ in Košice	2013 – up to now

VIII. - Overview of international mobilities and visits oriented on education and research/artistic/other activities in the given field of study

VIII.a - Name of the institution	VIII.b - Address of the institution	VIII.c - Duration (indicate the duration of stay)	VIII.d - Mobility scheme, employment contract, other (describe)
University of Texas Health Science Center at San Antonio	San Antonio, Texas, U.S.A.	May 2011 - August 2011	Postdoctoral Research Associate
University of Texas Health Science Center at San Antonio	San Antonio, Texas, U.S.A.	June 2008 - May 2010	Postdoctoral Research Associate
École Polytechnique Fédérale de Lausanne	Lausanne, Švajčiarsko	October 2004 - July 2005	Research Scholar

IX. - Other relevant facts

IX.a - If relevant, other activities related to higher education or research/artistic/other activities are mentioned

member of the Slovak Biophysical Society,

member of the Slovak Society for Biochemistry and Molecular Biology

Date of last update

2025-04-03